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1.
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11 p, 2.8 MB |
The feather epithelium contributes to the dissemination and ecology of clade 2.3.4.4b H5 high pathogenicity avian influenza viruses in ducks
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Gaide, Nicolas (Université de Toulouse) ;
Filaire, Fabien (THESEO France. LanXess Biosecurity) ;
Bertran, Kateri (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Crispo, Manuela (Université de Toulouse) ;
Dirat, Malorie (Université de Toulouse) ;
Secula, Aurélie (Université de Toulouse) ;
Foret-Lucas, Charlotte (Université de Toulouse) ;
Payré, Bruno (University of Toulouse) ;
Perlas Puente, Albert (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Majó i Masferrer, Natàlia (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Soubies, Sébastien (Université de Toulouse) ;
Guérin, Jean-Luc (Université de Toulouse)
Immature feathers are known replication sites for high pathogenicity avian influenza viruses (HPAIVs) in poultry. However, it is unclear whether feathers play an active role in viral transmission. This study aims to investigate the contribution of the feather epithelium to the dissemination of clade 2. [...]
2023 -  10.1080/22221751.2023.2272644
Emerging microbes & infections, Vol. 12 (november 2023)
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2.
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10 p, 1.9 MB |
Diverse infectivity, transmissibility, and pathobiology of clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses in chickens
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Kwon, Jung-Hoon (Kyungpook National University) ;
Bertran, Kateri (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Lee, Dong-Hun (Konkuk University) ;
Criado, Miria Ferreira (Auburn University) ;
Killmaster, Lindsay (U.S. National Poultry Research Center) ;
Pantin-Jackwood, Mary J. (U.S. National Poultry Research Center) ;
Swayne, David E. (U.S. National Poultry Research Center)
Clade 2. 3. 4. 4 Eurasian lineage H5Nx highly pathogenic avian influenza virus (HPAIV) has become the globally dominant clade and caused global outbreaks since 2014. The clade 2. 3. 4. 4 viruses have evolved into eight hemagglutinin subgroups (2. [...]
2023 - 10.1080/22221751.2023.2218945
Emerging microbes & infections, Vol. 12 (june 2023)
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3.
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4 p, 2.5 MB |
Experimental and field investigations of exposure, replication and transmission of SARS-CoV-2 in pigs in the Netherlands
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Sikkema, Reina S. (Erasmus Medical Centre) ;
Tobias, Tijs (Utrecht University) ;
Oreshkova, Nadia (Wageningen Bioveterinary Research) ;
de Bruin, Erwin (Erasmus Medical Centre) ;
Okba, Nisreen M. A (Erasmus Medical Centre) ;
Chandler, Felicity (Erasmus Medical Centre) ;
Hulst, Marcel M. (Wageningen Bioveterinary Research) ;
Rodon, Jordi (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Houben, Manon (Royal GD Animal Health) ;
van Maanen, Kees (Royal GD Animal Health) ;
Bultman, Hans (Royal GD Animal Health) ;
Meester, Marina (Utrecht University) ;
Gerhards, Nora M. (Wageningen Bioveterinary Research) ;
Bouwknegt, Martijn (Vion Food Group) ;
Urlings, Bert (Vion Food Group) ;
Haagmans, Bart L (Erasmus Medical Centre) ;
Kluytmans, Jan (University Medical Center Utrecht, Utrecht University) ;
Geurtsvankessel, Corine (Erasmus Medical Centre) ;
van der Poel, Wim H.M. (Wageningen Bioveterinary Research) ;
Koopmans, Marion P.G. (Erasmus Medical Centre) ;
Stegeman, Arjan (Utrecht University)
In order to assess the risk of SARS-CoV-2 infection, transmission and reservoir development in swine, we combined results of an experimental and two observational studies. First, intranasal and intratracheal challenge of eight pigs did not result in infection, based on clinical signs and PCR on swab and lung tissue samples. [...]
2021 - 10.1080/22221751.2021.2011625
Emerging microbes & infections, Vol. 11 (december 2021) , p. 91-94
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4.
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15 p, 3.3 MB |
Enhanced replication fitness of MERS-CoV clade B over clade A strains in camelids explains the dominance of clade B strains in the Arabian Peninsula
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Te, Nigeer (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Rodon, Jordi (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pérez, Mónica (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Vergara-Alert, Júlia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bensaid, Albert (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Middle East respiratory syndrome coronavirus (MERS-CoV) continues infecting humans and dromedary camels. While MERS-CoV strains from the Middle East region are subdivided into two clades (A and B), all the contemporary epidemic viruses belong to clade B. [...]
2021 - 10.1080/22221751.2021.2019559
Emerging microbes & infections, Vol. 11 (december 2021) , p. 260-274
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5.
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9 p, 1.2 MB |
Evidence of Zika virus horizontal and vertical transmission in Aedes albopictus from Spain but not infectious virus in saliva of the progeny
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Núñez García, Ana Isabel (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Talavera Forcades, Sandra (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Birnberg, Lotty (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Rivas, Raquel (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pujol, Núria (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Verdún, Marta (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Aranda Pallero, Carles (Consell Comarcal del Baix Llobregat. Servei de Control de Mosquits) ;
Berdugo, Miguel (Universitat Pompeu Fabra) ;
Busquets, Núria (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Aedes albopictus mosquitoes have been experimentally demonstrated to be a competent vector for Zika virus (ZIKV) in different countries, but there are still some gaps related to the importance of Ae. [...]
2020 - 10.1080/22221751.2020.1830718
Emerging microbes & infections, Vol. 9 (october 2020) , p. 2236-2244
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6.
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13 p, 3.0 MB |
Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients
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Andrés, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garcia-Cehic, D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gregori i Font, Josep (Roche Diagnostics SL (Sant Cugat del Valles)) ;
Piñana, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodríguez Frías, Francisco (Universitat Autònoma de Barcelona) ;
Guerrero Murillo, Mercedes (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esperalba, Juliana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ;
Goterris, Lidia (Hospital Universitari Vall d'Hebron) ;
Codina, María Gema (Hospital Universitari Vall d'Hebron) ;
Quer, Susanna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martín, Maria Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Almirante Gragera, Benito (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteban Mur, Juan Ignacio (Universitat Autònoma de Barcelona) ;
Pumarola Suñé, Tomàs (Universitat Autònoma de Barcelona) ;
Antón, Andrés (Universitat Autònoma de Barcelona) ;
Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The SARS-CoV-2 spike (S) protein, the viral mediator for binding and entry into the host cell, has sparked great interest as a target for vaccine development and treatments with neutralizing antibodies. [...]
2020 - 10.1080/22221751.2020.1806735
Emerging microbes & infections, Vol. 9 Núm. 1 (september 2020) , p. 1900-1911
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7.
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16 p, 2.0 MB |
ATP2, The essential P4-ATPase of malaria parasites, catalyzes lipid-stimulated ATP hydrolysis in complex with a Cdc50 β-subunit
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Lamy, Anaïs (Umeå University) ;
Macarini-Bruzaferro, Ewerton (University of São Paulo) ;
Dieudonné, Thibaud (Aarhus University) ;
Peralvarez-Marin, Alex (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Lenoir, Guillaume (Université Paris-Saclay, CEA, CNRS) ;
Montigny, Cédric (Université Paris-Saclay, CEA, CNRS) ;
le Maire, Marc (Université Paris-Saclay, CEA, CNRS) ;
Vázquez-Ibar, José Luis (Université Paris-Saclay, CEA, CNRS)
Gene targeting approaches have demonstrated the essential role for the malaria parasite of membrane transport proteins involved in lipid transport and in the maintenance of membrane lipid asymmetry, representing emerging oportunites for therapeutical intervention. [...]
2021 - 10.1080/22221751.2020.1870413
Emerging microbes & infections, Vol. 10 (january 2021) , p. 132-147
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8.
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10 p, 2.5 MB |
Population dynamics and antigenic drift of Bordetella pertussis following whole cell vaccine replacement, Barcelona, Spain, 1986-2015
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Mir-Cros, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Moreno-Mingorance, Albert (Hospital Universitari Vall d'Hebron) ;
Martin-Gomez, M. Teresa (Departament de Genètica i de Microbiologia) ;
Codina, María Gema (Hospital Universitari Vall d'Hebron) ;
Cornejo-Sánchez, Thais (Hospital Universitari Vall d'Hebron) ;
Rajadell Guiu, Mireia (Departament de Genètica i de Microbiologia) ;
Van Esso, Diego (Institut Català de la Salut) ;
Rodrigo Gonzalo de Líria, Carlos (Hospital Universitari Vall d'Hebron) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Jané i Checa, Mireia (Servei Català de la Salut) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Fàbrega-Santamaria, Anna (Universitat de Vic - Universitat Central de Catalunya) ;
González-López, Juanjo 1975- (Departament de Genètica i de Microbiologia) ;
Hospital Universitari Vall d'Hebron
Among the factors associated with the resurgence of whooping cough, special emphasis has been given to pathogen adaptation after the introduction of the acellular vaccine (ACV). To assess the impact of the vaccine transition strategy from whole-cell vaccine (WCV) to ACV on population dynamics of Bordetella pertussis in Barcelona (Spain), we studied 339 isolates collected from 1986 to 2015 by PFGE and multi-locus variable-number tandem repeat analysis (MLVA). [...]
2019 - 10.1080/22221751.2019.1694395
Emerging microbes & infections, Vol. 8 (november 2019) , p. 1711-1720
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9.
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11 p, 2.3 MB |
Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein
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Rodon, Jordi (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Okba, Nisreen M. A. (Erasmus Medical Centre. Department of Viroscience) ;
Te, Nigeer (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
van Dieren, Brenda (Utrecht University. Department of Infectious Diseases & Immunology) ;
Bosch, Berend-Jan (Utrecht University. Department of Infectious Diseases & Immunology) ;
Bensaid, Albert (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Haagmans, Bart L. (Erasmus Medical Centre. Department of Viroscience) ;
Vergara-Alert, Júlia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
The ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks pose a worldwide public health threat. Blocking MERS-CoV zoonotic transmission from dromedary camels, the animal reservoir, could potentially reduce the number of primary human cases. [...]
2019 - 10.1080/22221751.2019.1685912
Emerging microbes & infections, Vol. 8 (november 2019) , p. 1593-1603
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10.
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16 p, 21.0 MB |
Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and -independent regulatory pathways
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Martínez Torró, Carlos (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Torres Puig, Sergi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Monge, Marta (Vall d'Hebron Institut d'Oncologia) ;
Sánchez Alba, Lucía (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
González-Martín, Miguel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Marcos Silva, Marina (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Peralvarez-Marin, Alex (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Canals, Francesc (Vall d'Hebron Institut d'Oncologia) ;
Querol Murillo, Enrique (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Piñol Ribas, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Quijada Pich, Oscar (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Transition metals participate in numerous enzymatic reactions and they are essential for survival in all living organisms. For this reason, bacterial pathogens have evolved dedicated machineries to effectively compete with their hosts and scavenge metals at the site of infection. [...]
2020 - 10.1080/22221751.2019.1700762
Emerging microbes & infections, Vol. 9, issue 1 (Jan. 2020) , p. 5-19
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